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Ferroptosis Activation Contributes to Kidney Aging in Mice by Promoting Tubular Cell Senescence

26 Feb 2025

Abstract excerpt

Kidney aging is the strongest independent risk factor for chronic kidney disease. Ferroptosis, a recently discovered form of cell death mediated by iron overload and lipid peroxidation accumulation, has an unclear role in kidney aging. To determine the pathophysiological role of ferroptosis during kidney aging, we employed immunofluorescence, Western blotting, and qRT-PCR to analyze renal cells and tissues in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40036248
DOI: 10.1093/gerona/glaf042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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