Article

Longitudinal single cell RNA-sequencing reveals evolution of micro- and macro-states in chronic myeloid leukemia

2025-05-17

Abstract excerpt

<h4>ABSTRACT</h4> Single cell RNA sequencing (scRNA-seq) has revolutionized our understanding of cancer, yet identifying meaningful disease states from single cell data remains challenging. Here, we systematically explore the chronic myeloid leukemia (CML) specific information content encoded in single cell versus bulk transcriptomics to resolve this paradox and clarify how discrete disease-defining states emerge...

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Literature Corpus work: 59e19822-95d0-5041-a065-565ddecf2516
DOI: 10.1101/2025.05.14.653262

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