Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes.

BMB reports - 1 Oct 2015

Byun Hae-Ok, Lee Young-Kyoung, Kim Jeong-Min, Yoon Gyesoon

Abstract excerpt

Cellular senescence is a process by which cells enter a state of permanent cell cycle arrest. It is commonly believed to underlie organismal aging and age-associated diseases. However, the mechanism by which cellular senescence contributes to aging and age-associated pathologies remains unclear. Recent studies showed that senescent cells exert detrimental effects on the tissue microenvironment, generating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Cellular Senescence
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Retinoids in leukemia and cellular processes

Share to Secretory Pathway

Share to Telomeres, Telomerase, and Senescence

Source

Open in PubMed Open full text

Identifiers

PMID: 26129674
DOI: 10.5483/bmbrep.2015.48.10.122
PMCID: PMC4911181

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes.PMID 26129674Read ↗

Cellular senescence and the senescent secretory phenotype in age-related chronic diseases.Semantic proximity Read ↗

Impact of senescence-associated secretory phenotype and its potential as a therapeutic target for senescence-associated diseases.Semantic proximity Read ↗

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.Semantic proximity Read ↗

[Involvement of phenotype secretor of senescent cells in the development of cancer, aging and the diseases associated with age].Semantic proximity Read ↗

Dynamic and scalable assessment of the senescence-associated secretory phenotype (SASP).Semantic proximity Read ↗

Senescent cells at the crossroads of aging, disease, and tissue homeostasisSemantic proximity Read ↗

The Senescence-Associated Secretory Phenotype (SASP) in the Challenging Future of Cancer Therapy and Age-Related DiseasesSemantic proximity Read ↗

The role of the dynamic epigenetic landscape in senescence: orchestrating SASP expressionSemantic proximity Read ↗

Cellular senescence: Molecular mechanisms and pathogenicitySemantic proximity Read ↗

“Social Life” of Senescent Cells: What Is SASP and Why Study It?Semantic proximity Read ↗

Regulation of cell function and identity by cellular senescenceSemantic proximity Read ↗

Senescence and senolysis in cancer: The latest findingsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.