Article

Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage

2024-02-13

Abstract excerpt

Pairwise compatibility between virus and host proteins can dictate the outcome of infection. During transmission, both inter- and intraspecies variabilities in receptor protein sequences can impact cell susceptibility. Many viruses possess mutable viral entry proteins and the patterns of host compatibility can shift as the viral protein sequence changes. This combinatorial sequence space between virus and host is...

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Literature Corpus work: 2c6ba6ef-5bd5-5ec8-ac8c-181be696fffb
DOI: 10.1101/2024.02.13.580056

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