Article

Beyond Generic Signal Peptides: ApexSP Enables Cargo-Specific Secretion Design

2026-07-30

Abstract excerpt

Recombinant proteins are widely used in biopharmaceuticals, industrial manufacturing, and molecular diagnostics; however, efficient secretion remains a major bottleneck limiting their large scale production. As core elements controlling protein entry into secretion pathways, signal peptides do not function solely based on their own sequences, but rather depend on coordinated compatibility among cargo protein prope...

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Literature Corpus work: 2c614aa7-ab53-57c5-88b1-38012c99660d
DOI: 10.64898/2026.07.29.741461

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