Article

Consideration of a Liquid mutation-accumulation Experiment to Measure Mutation Rates by Successive Serial Dilution

2023-09-01

Abstract excerpt

The mutation-accumulation (MA) experiment is a fixture of evolutionary biology, though it is laborious to perform. MA experiments typically take between months and years to acquire sufficient mutations to measure DNA mutation rates and mutation spectra. MA experiments for many organisms rely on colony formation on agar plates and repetitive streaking, an environment which at first glance appears somewhat contrived...

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Literature Corpus work: 2c134950-42b9-5d6c-ba1b-9ddc8c61ef3f
DOI: 10.1101/2023.08.31.555790

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