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Method for Detecting and Studying Genome-Wide Mutations in Single Living Cells in Real Time.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Elez Marina, Robert Lydia, Matic Ivan

Abstract excerpt

DNA sequencing and fluctuation test have been choice methods for studying DNA mutations for decades. Although invaluable tools allowing many important discoveries on mutations, they are both highly influenced by fitness effects of mutations, and therefore suffer several limits. Fluctuation test is for example limited to mutations that produce an identifiable phenotype, which is the minority of all generated...

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PMID: 29322456
DOI: 10.1007/978-1-4939-7638-6_3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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