A continuous-time model to correct for selection in mutation accumulation experiments.

Abstract excerpt

Mutation accumulation (MA) experiments are crucial for understanding evolution. In microbial populations, these experiments typically involve periods of population growth, where a single individual forms a visible colony, followed by severe bottlenecks. Studies on the effects of positive and negative selection in MA experiments have shown that, even with as few as ten generations of growth between bottlenecks,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Models, Genetic
• Share to Mutation
• Share to Mutation Accumulation