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Article

Fatty acid synthase modulates homeostatic responses to myocardial stress.

The Journal of biological chemistry - 2 Sept 2011

Razani Babak, Zhang Haixia, Schulze P Christian, Schilling Joel D, Verbsky John, Lodhi Irfan J, Topkara Veli K, Feng Chu, Coleman Trey, Kovacs Attila, Kelly Daniel P, Saffitz Jeffrey E, Dorn Gerald W, Nichols Colin G, Semenkovich Clay F

Abstract excerpt

Fatty acid synthase (FAS) promotes energy storage through de novo lipogenesis and participates in signaling by the nuclear receptor PPARα in noncardiac tissues. To determine if de novo lipogenesis is relevant to cardiac physiology, we generated and characterized FAS knockout in the myocardium (FA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21757749
DOI: 10.1074/jbc.M111.230508
PMCID: PMC3162454

Genes

FAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21757749-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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