Article
Stabilisation of HIF signalling extends epicardial activation and neonatal heart regeneration
2023-01-26
Abstract excerpt
<title>Abstract</title> <p> In humans, new-born infants have the ability to regenerate their heart during early life. This is modelled in the mouse, where regenerative capacity is maintained for the first week after birth but lost thereafter. Reactivation of this process holds significant therapeutic potential, however, the molecular pathways that might be targeted to extend neonatal regeneration remain elusive....
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Identifiers and source
- Literature Corpus work
- 2bff897c-66e2-5910-97f3-04c070de50ed
- DOI
- 10.21203/rs.3.rs-2496938/v1