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The epicardium signals the way towards heart regeneration

29 Apr 2014

Abstract excerpt

From historical studies of developing chick hearts to recent advances in regenerative injury models, the epicardium has arisen as a key player in heart genesis and repair. The epicardium provides paracrine signals to nurture growth of the developing heart from mid-gestation, and epicardium-derived cells act as progenitors of numerous cardiac cell types. Interference with either process is terminal for heart...

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Identifiers

PMID: 24933704
DOI: 10.1016/j.scr.2014.04.007

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