Article
Stabilisation of HIF signalling in the mouse epicardium extends embryonic potential and neonatal heart regeneration
2025-08-28
Abstract excerpt
<title>Abstract</title> <p> In humans, new-born infants can regenerate their heart during early life. This is modelled in the mouse, where regenerative capacity is maintained for the first week after birth but lost thereafter. Reactivation of this process holds great therapeutic potential; however, the molecular pathways that might be targeted to extend neonatal regeneration remain elusive. Here, we explored a r...
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Identifiers and source
- Literature Corpus work
- 1f9ec5e6-a2a8-56a9-91b1-7b21231be92e
- DOI
- 10.21203/rs.3.rs-2496938/v3