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Regenerative and non-regenerative transcriptional states of the human epicardium: from foetus to adult and back again

2021-10-12

Abstract excerpt

<h4>ABSTRACT</h4> Epicardial activation appears to be required for cardiac regeneration. Although reverting quiescent adult epicardium to an active neonatal or foetal state will likely represent a key therapeutic approach for human cardiac regeneration, the exact molecular differences between human adult and foetal epicardium are not understood. We used single-cell RNA sequencing to compare epicardial cells from...

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Literature Corpus work
cafcb1ac-0dc4-5730-a044-ac2633497911
DOI
10.1101/2021.10.11.462541
Open publication

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Regenerative and non-regenerative transcriptional states of the human epicardium: from foetus to adult and back againDOI 10.1101/2021.10.11.462541
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