Article

Spatially resolved transcriptomics reveals the architecture of the tumor/microenvironment interface

2020-11-05

Abstract excerpt

<h4>SUMMARY</h4> During tumor progression, cancer cells come into contact with novel non-tumor cell types, but it is unclear how tumors adapt to these new environments. Here, we integrate spatially resolved transcriptomics, single-cell RNA-seq, and single-nucleus RNA-seq to characterize tumor-microenvironment interactions at the tumor boundary. Using a zebrafish model of melanoma, we identify a distinct “interfac...

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Literature Corpus work: abebe38c-fdba-56fa-aad2-b4035b24bd11
DOI: 10.1101/2020.11.05.368753

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