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Single-cell RNA sequencing in melanoma: what have we learned so far?

21 Jan 2024

Abstract excerpt

Over the past decade, there have been remarkable improvements in the treatment and survival rates of melanoma patients. Treatment resistance remains a persistent challenge, however, and is partly attributable to intratumoural heterogeneity. Melanoma cells can transition through a series of phenotypic and transcriptional cell states that vary in invasiveness and treatment responsiveness. The diverse stromal and...

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PMID: 38241976
DOI: 10.1016/j.ebiom.2024.104969

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