Article

Creating cell-specific computational models of stem cell-derived cardiomyocytes using optical experiments

2024-01-08

Abstract excerpt

Human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have gained traction as a powerful model in cardiac disease and therapeutics research, since iPSCs are self-renewing and can be derived from healthy and diseased patients without invasive surgery. However, current iPSC-CM differentiation methods produce cardiomyocytes with immature, fetal-like electrophysiological phenotypes, and the variety of...

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Literature Corpus work: 2bc22e0f-075a-5e44-bb7e-5a65944033c3
DOI: 10.1101/2024.01.07.574577

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