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Ion channel expression and electrophysiology of singular human (primary and induced pluripotent stem cell derived) cardiomyocytes

2021-03-04

Abstract excerpt

<h4> SUMMARY </h4> Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) and primary human cardiomyocytes are used for in vitro cardiac safety testing. hiPSC-CMs have been associated with a vast heterogeneity regarding single-cell morphology, beating behavior and action potential duration, prompting a systematic analysis of single-cell characteristics. Previously published hiPSC-CM studies reve...

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Literature Corpus work
9af1e40f-1c00-5fe9-bd00-0260e62c367a
DOI
10.1101/2021.03.04.433834
Open publication

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Ion channel expression and electrophysiology of singular human (primary and induced pluripotent stem cell derived) cardiomyocytesDOI 10.1101/2021.03.04.433834
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