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Improved computational identification of drug response using optical measurements of human stem cell derived cardiomyocytes in microphysiological systems

2019-10-01

Abstract excerpt

Cardiomyocytes derived from human induced pluripotent stem cells hold great potential for drug screening applications. However, their usefulness is limited by the relative immaturity of cells’ electro-physiological properties as compared to native cardiomyocytes in the adult human heart. In this work, we extend and improve on methodology to address this limitation, building on previously introduced computational p...

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Literature Corpus work
761f64f2-9cea-5750-8f01-649ee14f18bd
DOI
10.1101/787390
Open publication

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Improved computational identification of drug response using optical measurements of human stem cell derived cardiomyocytes in microphysiological systemsDOI 10.1101/787390
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