Article

In silico prediction of ARB resistance: A first step in creating personalized ARB therapy

2020-02-12

Abstract excerpt

Angiotensin II type 1 receptor (AT 1 R) blockers (ARBs) are among the most prescribed drugs. However, ARB effectiveness varies widely, and some patients do not respond to ARB therapy. One reason for the variability between patients is non-synonymous single nucleotide polymorphisms (nsSNPs) within agtr1 , the AT 1 R gene. There are over 100 nsSNPs in the AT 1 R; therefore, this study embarked on determining whi...

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Literature Corpus work: 2b847811-a7ee-5ebd-ab5f-c7ba439d5bf3
DOI: 10.1101/2020.02.12.945402

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