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Article

Structure-Based Analysis of Single Nucleotide Variants in the Renin-Angiotensinogen Complex.

Global heart - 1 Jun 2017

Brown David K, Sheik Amamuddy Olivier, Tastan Bishop Özlem

Abstract excerpt

BACKGROUND: The renin-angiotensin system (RAS) plays an important role in regulating blood pressure and controlling sodium levels in the blood. Hyperactivity of this system has been linked to numerous conditions including hypertension, kidney disease, and congestive heart failure. Three classes of drugs have been developed to inhibit RAS. In this study, we provide a structure-based analysis of the effect of...

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Identifiers

PMID: 28302554
DOI: 10.1016/j.gheart.2017.01.006
PMCID: PMC5583000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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