Article

Mapping spatially-resolved transcriptomes in systemic sclerosis

2025-01-19

Abstract excerpt

Systemic sclerosis (SSc) is a prototypical fibrotic disease with high mortality and limited treatment options. Despite advances in single-cell RNA sequencing (scRNA-seq), the comprehensive understanding of cellular heterogeneity and cell-cell interaction within the fibrogenesis microenvironment remains limited. We generated spatially resolved transcriptome maps from healthy and SSc skin and built a scRNA-seq atlas...

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Literature Corpus work: b36164c6-5660-5a7f-915c-d012203d2239
DOI: 10.1101/2025.01.14.632962

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