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Article

Dissecting the Heterogeneity of Skin Gene Expression Patterns in Systemic Sclerosis

3 Aug 2015

Abstract excerpt

OBJECTIVE: To examine the heterogeneity of global transcriptome patterns in systemic sclerosis (SSc) skin in a large sample of patients with SSc and control subjects. METHODS: Skin biopsy specimens obtained from 61 patients enrolled in the Genetics versus Environment in Scleroderma Outcome Study (GENISOS) cohort and 36 unaffected control subjects with a similar demographic background were examined by Illumina...

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PMID: 26238292
DOI: 10.1002/art.39289

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