Article

Dopamine vesicles are specified by mechanisms overriding canonical synaptic vesicle size constraints

2026-03-02

Abstract excerpt

<h4>ABSTRACT</h4> Dopaminergic neurons contain distinct synaptic vesicle (SV) populations that segregate dopamine from glutamate, but the molecular basis of this segregation remains unclear. Using an established in vitro SV reconstitution system in fibroblasts, we show that synaptogyrin family proteins—synaptogyrin 1, synaptogyrin 2 and synaptogyrin 3—but not synaptophysin, selectively associate with VMAT2-positi...

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Literature Corpus work: 2a903163-bc32-54b1-a710-6423b9f17b73
DOI: 10.64898/2026.02.27.708430

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