Article

Prediction and Validation of Circulating G-quadruplex as a Novel Biomarker in Colorectal Cancer

2022-10-17

Abstract excerpt

<h4>Background: </h4> G-quadruplex (G4) is a special structure in DNA and RNA. It plays an important biological role in the formation of tumors via the Hoogsteen hydrogen base-pairing to form a planar array structure. G4 mutation prediction in the genome using bioinformatics revealed that the G4 quantity in SW480 cells was lower than that of the reference gene, but it was unclear how the G4 quantity was changed in...

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Literature Corpus work: 2a74c9cf-53a5-539b-82eb-bcd3d724cf17
DOI: 10.21203/rs.3.rs-2089648/v1

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