Guide for phenotype-specific profiling of DNA G-quadruplex-regulated genes.

Abstract excerpt

DNA G-quadruplex (G4) is a non-canonical four-stranded secondary structure that has been shown to play a role in epigenetic modulation of gene expression. Here, we present a primer on phenotype-specific profiling of DNA G-quadruplex-regulated genes. We provide guidance on in silico exploration of G4-related genes and phenotypes, and in vitro and in vivo validation of the relationship between G4 and phenotype. We...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to DNA
• Share to G-Quadruplexes
• Share to Phenotype