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African ancestry-enriched variants in the <i>GATM</i> gene are associated with elevated serum creatinine levels

2025-03-10

Abstract excerpt

<h4>Background</h4> Serum creatinine (Scr) levels are routinely used to estimate kidney function and health. Individuals of African ancestry have higher Scr levels – controlling for differences in age, sex, size, kidney function, and disease status – compared to individuals from other ancestral backgrounds. The reason for this difference is unknown. We hypothesized that there may be genetic variants found at rela...

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Literature Corpus work
2a025c30-f169-5882-ae32-e1e8a03c17ac
DOI
10.1101/2025.03.07.25323581
Open publication

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African ancestry-enriched variants in the <i>GATM</i> gene are associated with elevated serum creatinine levelsDOI 10.1101/2025.03.07.25323581
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