Article

Heterogeneous Nuclear Ribonucleoprotein C is an Indispensable Target in Acute Myeloid Leukemia

2023-10-03

Abstract excerpt

<h4>ABSTRACT</h4> Refractory disease is the greatest challenge in acute myeloid leukaemia (AML). Previously, we found vascular-associated AML cells as a source for refractory disease. In this study we use a bioassay of AML cells co-cultured on bone marrow-derived endothelial cells (BMECs) to screen 31 million compounds within a mixture-based synthetic combinatorial library followed by deconvolution leading to the...

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Literature Corpus work: 29ec7fe0-a328-5232-81ae-92c6591038d5
DOI: 10.1101/2023.10.02.559746

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