Article

Predicting efficiency of writing short sequences into the genome using prime editing

2021-11-10

Abstract excerpt

<h4>SUMMARY</h4> Short sequences can be precisely written into a selected genomic target using prime editing. This ability facilitates protein tagging, correction of pathogenic deletions, and many other exciting applications. However, it remains unclear what types of sequences prime editors can easily insert, and how to choose optimal reagents for a desired outcome. To characterize features that influence inserti...

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Literature Corpus work: c9b244ca-5b90-506e-add2-3468117445bc
DOI: 10.1101/2021.11.10.468024

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