Article

InstructPLM: Aligning Protein Language Models to Follow Protein Structure Instructions

2024-04-20

Abstract excerpt

Large language models are renowned for their efficacy in capturing intricate patterns, including co-evolutionary relationships, and underlying protein languages. However, current methodologies often fall short in illustrating the emergence of genomic insertions, duplications, and insertion/deletions (indels), which account for approximately 14% of human pathogenic mutations. Given that structure dictates function,...

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Literature Corpus work: 32beb7ee-9956-5611-9d90-bb690097c3b3
DOI: 10.1101/2024.04.17.589642

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