Article

Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring

2023-06-12

Abstract excerpt

The basal breast cancer subtype is enriched for triple-negative breast cancer (TNBC) and displays consistent large chromosomal deletions. Here, we characterize the evolution and maintenance of chromosome 4p (chr4p) loss in basal breast cancer. TCGA data analysis showed recurrent deletion of chr4p in basal breast cancer. Phylogenetic analysis of a unique panel of 23 primary tumor/patient-derived xenograft basal bre...

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Literature Corpus work: 294b37a7-3e99-550e-8259-3fbcbd0aa792
DOI: 10.1101/2023.06.10.544434

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