Article
Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast.
The Journal of pathology - 1 Apr 2014
Natrajan Rachael, Wilkerson Paul M, Marchiò Caterina, Piscuoglio Salvatore, Ng Charlotte K Y, Wai Patty, Lambros Maryou B, Samartzis Eleftherios P, Dedes Konstantin J, Frankum Jessica, Bajrami Ilirjana, Kopec Alicja, Mackay Alan, A'hern Roger, Fenwick Kerry, Kozarewa Iwanka, Hakas Jarle, Mitsopoulos Costas, Hardisson David, Lord Christopher J, Kumar-Sinha Chandan, Ashworth Alan, Weigelt Britta, Sapino Anna, Chinnaiyan Arul M, Maher Christopher A, Reis-Filho Jorge S
Abstract excerpt
Micropapillary carcinoma (MPC) is a rare histological special type of breast cancer, characterized by an aggressive clinical behaviour and a pattern of copy number aberrations (CNAs) distinct from that of grade- and oestrogen receptor (ER)-matched invasive carcinomas of no special type (IC-NSTs). The aims of this study were to determine whether MPCs are underpinned by a recurrent fusion gene(s) or mutations in...
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