Article
Mathematical modelling of cancer invasion: Phenotypic transitioning provides insight into multifocal foci formation
2023-11-20
Abstract excerpt
The transition from the epithelial to mesenchymal phenotype and its reverse (from mesenchymal to epithelial) are crucial processes necessary for the progression and spread of cancer. In this paper, we investigate how phenotypic switching at the cancer cell level impacts the behaviour at the tissue level, specifically on the emergence of isolated foci of the invading solid tumour mass leading to a multifocal tumour...
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Identifiers and source
- Literature Corpus work
- 2941f746-6c75-5cfc-988f-242edbbb1d30
- DOI
- 10.1016/j.jocs.2023.102175