Article

Understanding and leveraging phenotypic plasticity during metastasis formation

2022-11-07

Abstract excerpt

Cancer metastasis is the process of detrimental systemic spread and the primary cause of cancer-related fatalities. Successful metastasis formation requires tumor cells to be proliferative and invasive; however, cells cannot be effective at both tasks simultaneously. Tumor cells compensate for this trade-off by changing their phenotype during metastasis formation through phenotypic plasticity. Given the changing s...

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Literature Corpus work: 03a81129-6000-5278-922d-a226082d6ee4
DOI: 10.1101/2022.11.07.515430

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