Article
Epithelial-mesenchymal plasticity: How have quantitative mathematical models helped improve our understanding?
2017-03-29
Abstract excerpt
Phenotypic plasticity, the ability of cells to reversibly alter their phenotypes in response to signals, presents a significant clinical challenge to treating solid tumors. Tumor cells utilize phenotypic plasticity to evade therapies, metastasize, and colonize distant organs. As a result, phenotypic plasticity can accelerate tumor progression. A well-studied example of phenotypic plasticity is the bidirectional co...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 0b090cc7-fbf1-55bd-8a07-ed39c04ae148
- DOI
- 10.1101/122036