Article
Tumor morphological evolution: directed migration and gain and loss of the self-metastatic phenotype.
Biology direct - 20 Apr 2010
Enderling Heiko, Hlatky Lynn, Hahnfeldt Philip
Abstract excerpt
BACKGROUND: Aside from the stepwise genetic alterations known to underlie cancer cell creation, the microenvironment is known to profoundly influence subsequent tumor development, morphology and metastasis. Invasive cluster formation has been assumed to be dependent on directed migration and a he...
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