Article
HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long reads.
Genome research - 1 Sept 2020
Nurk Sergey, Walenz Brian P, Rhie Arang, Vollger Mitchell R, Logsdon Glennis A, Grothe Robert, Miga Karen H, Eichler Evan E, Phillippy Adam M, Koren Sergey
Abstract excerpt
Complete and accurate genome assemblies form the basis of most downstream genomic analyses and are of critical importance. Recent genome assembly projects have relied on a combination of noisy long-read sequencing and accurate short-read sequencing, with the former offering greater assembly continuity and the latter providing higher consensus accuracy. The recently introduced Pacific Biosciences (PacBio) HiFi...
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