Article

MAFB drives differentiation by permitting WT1 binding to podocyte specific promoters

2023-09-07

Abstract excerpt

Podocytes are highly specialized cells, but their chromatin status and the precise molecular events leading to their differentiation remain poorly defined. Here we used ChIP-Seq analysis for H3K4me3, H3K4me1 and H3K27me3 to establish the histone methylation map in adult mouse podocytes. Our data demonstrate open chromatin across podocyte specific genes and reveals that genes expressed in the mesoderm lineage becom...

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Literature Corpus work: 2922332c-a6db-588c-a85c-e7990c79d186
DOI: 10.1101/2023.09.06.555670

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