Article

Single-cell chromatin and gene-regulatory dynamics of mouse nephron progenitors

2021-10-14

Abstract excerpt

<h4>STRUCTURED ABSTRACT</h4> <h4>Background</h4> Cis-regulatory elements (CREs), such as enhancers and promoters, and their cognate transcription factors play a central role in cell fate specification. Bulk analysis of CREs has provided insights into gene regulation in nephron progenitor cells (NPCs). However, the cellular resolution required to unravel the dynamic changes in regulatory elements associated with...

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Literature Corpus work: 732a453d-abca-523a-9dfd-7f51a730154c
DOI: 10.1101/2021.10.13.464099

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