Article

Spatially Resolved Microglial State Transitions Govern Strain-Specific Zika Neuropathogenesis

2026-05-05

Abstract excerpt

Neurotropic viruses disrupt brain homeostasis through complex interactions among infected cells, resident immune responses, and tissue architecture, yet how these processes unfold across space, time, and cell types, and how viral strain differences shape disease severity, remains poorly understood. Here, we integrate high-resolution spatial transcriptomics with infection-aware cell-type profiling to construct a sp...

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Literature Corpus work: 28fb3d8e-fed5-5c5c-b9e0-7f0b40b9a5bf
DOI: 10.64898/2026.04.30.721456

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Spatially Resolved Microglial State Transitions Govern Strain-Specific Zika NeuropathogenesisDOI 10.64898/2026.04.30.721456Read

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