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Zika virus infection reprograms global transcription of host cells to allow sustained infection

1 Jan 2017

Abstract excerpt

Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenital microcephaly and Guillain-Barré syndrome. There are currently no targeted therapies for ZIKV infection. To identify novel antiviral targets and to elucidate the mechanisms by which ZIKV exploits the host cell machinery to support sustained replication, we analyzed the transcriptomic landscape of human microglia,...

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PMID: 28442752
DOI: 10.1038/emi.2017.9

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