Article

High interleukin-3 concentrations prime murine myeloid progenitor cells towards granulocytic differentiation

2024-01-24

Abstract excerpt

Impaired differentiation a key feature of many hematopoietic malignancies. To decipher the molecular processes underlying malignant transformation, it is important to understand the mechanisms regulating hematopoietic differentiation. Cell lines derived from transformed hematopoietic progenitors or from leukemia patients have proven to be valuable model systems for mechanistic investigations of hematopoiesis. In t...

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Literature Corpus work: 28ec2152-17d4-5ebf-99d1-65db7d441dfd
DOI: 10.1101/2024.01.24.576972

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