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Article

Characterization of a factor-dependent acute leukemia cell line with translocation (3;3)(q21;q26).

Blood - 1 Oct 1990

Oval J, Jones O W, Montoya M, Taetle R

Abstract excerpt

A strictly factor-dependent cell line (UCSD/AML1) was established from a patient with the syndrome of multilineage acute leukemia with high platelets. The patient's cells and the cell line karyotype were 45,XX,-7,t(3;3)(q21;q26), typical of the syndrome of acute leukemia with high platelets. The cell line expresses CD34, CD7, TdT, and myeloid (CD13, CD14, CD33) and megakaryocyte/platelet (CD36, CD41, CD42b,...

Topics

Acute Disease
Aged
Antigens, CD7
Antigens, Differentiation, T-Lymphocyte
Cell Transformation, Neoplastic
Chromosomes, Human, Pair 3
Female
Granulocyte-Macrophage Colony-Stimulating Factor
Hematopoiesis
Hematopoietic Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Interleukin-3

Interleukin-4

Interleukin-6

Leukemia

Macrophage Colony-Stimulating Factor

Megakaryocytes

Phenotype

Source

Identifiers

PMID: 1698479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1698479-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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