Article

Real-time chromatin dynamics at the single gene level during transcription activation

2017-02-23

Abstract excerpt

Genome dynamics relate to regulation of gene expression, the most fundamental process in biology. Yet we still do not know whether the very process of transcription drives spatial organization and chromatin conformation at specific gene loci. To address this issue, we have optimized the ANCHOR/ParB DNA labeling system for real-time imaging and quantitative analysis of the dynamics of a single-copy transgene in hum...

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Literature Corpus work: 28e17e89-10f2-5006-9731-54ad6a75f132
DOI: 10.1101/111179

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