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Article

Geny: a genotyping tool for allelic decomposition of killer cell immunoglobulin-like receptor genes.

Frontiers in immunology - 1 Jan 2024

Zhou Qinghui, Ghezelji Mazyar, Hari Ananth, Ford Michael K B, Holley Connor, Sahinalp S Cenk, Numanagić Ibrahim

Abstract excerpt

Introduction: Accurate genotyping of Killer cell Immunoglobulin-like Receptor (KIR) genes plays a pivotal role in enhancing our understanding of innate immune responses, disease correlations, and the advancement of personalized medicine. However, due to the high variability of the KIR region and high level of sequence similarity among different KIR genes, the generic genotyping workflows are unable to accurately...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39763645
DOI: 10.3389/fimmu.2024.1494995
PMCID: PMC11701374

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