Article

Cooperativity of catalytic and lectin-like domain of <i>T. congolense</i> trans-sialidase modulates its catalytic activity

2021-05-28

Abstract excerpt

Trans-sialidases (TS) represent a multi-gene family of unusual enzymes, which catalyse the transfer of terminal sialic acids from sialoglycoconjugates to terminal galactose or N -acetylgalactosamine residues of oligosaccharides without the requirement of CMP-Neu5Ac, the activated Sia used by typical sialyltransferases. Most work on trypanosomal TS has been done on enzymatic activities of TS from T. cruzi (causin...

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Literature Corpus work: 28b66ec1-99bb-52d4-8fc6-d0d9905d7be7
DOI: 10.1101/2021.05.28.446113

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Cooperativity of catalytic and lectin-like domain of <i>T. congolense</i> trans-sialidase modulates its catalytic activityDOI 10.1101/2021.05.28.446113Read

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