Article

Endogenous SIRT3 activity is dispensable for normal hearing recovery after noise exposure in young adult mice

2020-02-10

Abstract excerpt

<h4>ABSTRACT</h4> Occupational noise-induced hearing loss (NIHL) affects millions of people worldwide and presents a large social and personal burden. Some genetic variants in the mitochondrial oxidative stress response correlate strongly with susceptibility to NIHL in both humans and mice. Here we test the hypothesis that SIRT3, a regulator of the mitochondrial oxidative stress response, is required in mice for...

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Literature Corpus work: 289a9b8e-5939-5f6b-a436-9f46d523cb75
DOI: 10.1101/2020.02.05.935882

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