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Article

Maintaining good hearing: calorie restriction, Sirt3, and glutathione.

Experimental gerontology - 1 Oct 2013

Han Chul, Someya Shinichi

Abstract excerpt

Reducing calorie intake extends the lifespan of a variety of experimental models and delays progression of age-related hearing loss (AHL). AHL is a common feature of aging and is characterized by age-related decline of hearing associated with loss of sensory hair cells, spiral ganglion neurons, and/or stria vascularis degeneration in the cochlea. Sirtuins are a family of NAD(+)-dependent enzymes that regulate...

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Source

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Identifiers

PMID: 23454634
DOI: 10.1016/j.exger.2013.02.014
PMCID: PMC3759555

Genes

SIRT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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