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Article

Unraveling the influence of body mass index on complex diseases in East Asians: Insights from Mendelian randomization phenome-wide association study.

Medicine - 27 Jun 2025

Wu Ben, Li Weixin, Xu Shuling, Chen Rumeng, Ding Yining, Xu Rong, Wu Zhu, Bao Meihua, He Binsheng, Li Sen

Abstract excerpt

Studies on the relationship between body mass index (BMI) and different disease phenotypes have either not included systematic causal inference or have mostly focused on European populations. This highlights the importance of conducting Mendelian randomization (MR) phenome-wide association study to explore the associations between BMI and various diseases in East Asian populations. MR phenome-wide association...

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Identifiers

PMID: 40587687
DOI: 10.1097/MD.0000000000042998
PMCID: PMC12212858

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