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Supplementation via DAF-16 and <i>pnk-1</i> driven pantothenate–coenzyme A flux improves disease related stress resistance in <i>C. elegans</i>

2026-07-13

Abstract excerpt

Metabolic pathways are increasingly recognized as tractable targets in aging and disease. Building on prior work demonstrating that supplementation with low–molecular weight metabolites (amino acids, vitamins, and their intermediates) can extend lifespan in Caenorhabditis elegans , we focused on pantothenate (vitamin B 5 ), which is dysregulated in sarcopenic muscle and in several neurodegenerative and metabolic...

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Literature Corpus work
284c9a72-8889-52bd-a671-52a115b55e48
DOI
10.64898/2026.07.08.737381
Open publication

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Supplementation via DAF-16 and <i>pnk-1</i> driven pantothenate–coenzyme A flux improves disease related stress resistance in <i>C. elegans</i>DOI 10.64898/2026.07.08.737381
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