Article

Transcriptome-wide association study and fly experiments uncover the role of <i>CoA synthase</i> in ageing across species

2026-02-04

Abstract excerpt

While significant progress has been made in understanding the genetic architecture of ageing in model organisms, our understanding of human ageing remains limited. We performed a multi-tissue Transcriptome-wide association study (TWAS) on human lifespan, integrating GWAS data from >1 million parental lifespans with gene expression prediction models derived from reference transcriptomic datasets; followed by replic...

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Literature Corpus work: f4ec689a-a54c-51f0-8769-fd3312b25af5
DOI: 10.64898/2026.02.02.703301

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